Nursing Nerds

High-Yield Pharmacology

Book 04 · Page 1414 / 15

Question Set B: Matrix, Drop-Down, and Bowtie

Figure brief · not yet drawn

Three empty item shells drawn side by side as furniture: a matrix grid with radio cells, a cloze sentence with four drop-down chevrons, and a bowtie frame with five-box wings around a single center box.

Item 7 · MATRIX. A 61-year-old client is receiving prednisone, a corticosteroid, and enalapril, an angiotensin-converting enzyme inhibitor. Classify each finding. Scored per row.

FindingExpectedUnexpectedRequires immediate follow-up
a. Fasting blood glucose 148, up from 96 on admission
b. New dry, nonproductive cough
c. Increased appetite and difficulty sleeping
d. White patches on the tongue and buccal mucosa
e. Serum creatinine 1.5, up from 0.9 seven days ago
f. Swelling of the lips and tongue with a muffled voice
g. Potassium 6.1 with tall peaked T waves on the monitor
h. Black, tarry stool

Item 8 · DROP-DOWN CLOZE. Complete the passage. Delafloxacin, a fluoroquinolone, kills bacteria by inhibiting [8a]. Because the class carries a boxed warning for [8b], the nurse teaches the client to [8c], and to separate each dose from [8d]. 8a 1. bacterial cell wall cross-linking · 2. bacterial DNA gyrase and topoisomerase IV · 3. the 30S ribosomal subunit · 4. bacterial folate synthesis 8b 1. tendinitis and tendon rupture · 2. lactic acidosis · 3. severe liver injury · 4. pulmonary fibrosis 8c 1. stop the drug and call the prescriber for new heel or shoulder pain · 2. massage the painful area and finish the course · 3. take an over-the-counter anti-inflammatory for the pain · 4. take two doses together after a missed dose 8d 1. high-protein meals · 2. antacids and iron or calcium supplements · 3. all fluids for 2 hours · 4. acidic fruit juices

Item 9 · BOWTIE. A 74-year-old client who takes warfarin for atrial fibrillation fell 2 days ago. The client now has a severe headache, new left-sided weakness, and a blood pressure of 176/94. The international normalized ratio is 5.8.

Center · the condition the client is most likely experiencing: intracranial bleeding in the setting of excessive anticoagulation.

Left wing · select 2 actions to take:

  1. Hold all anticoagulant doses and notify the prescriber immediately
  2. Administer phytonadione and prepare for four-factor prothrombin complex concentrate as ordered
  3. Ambulate the client in the hallway to evaluate the weakness
  4. Give the scheduled warfarin dose and document the headache
  5. Apply ice to the head and reassess in 4 hours

Right wing · select 2 parameters to monitor:

  1. Level of consciousness and pupil response
  2. Serial international normalized ratio and hemoglobin
  3. Daily weight
  4. Bowel sounds every shift
  5. Capillary blood glucose before meals

Item 7 — Answers: a Expected, b Expected, c Expected, d Unexpected, e Unexpected, f Immediate, g Immediate, h Immediate Why a is expected: corticosteroids raise blood glucose by design of their metabolic action. Why b is expected: bradykinin accumulation on an angiotensin-converting enzyme inhibitor produces a dry cough. Why c is expected: appetite increase and insomnia are common early corticosteroid effects. Why d is unexpected: oral candidiasis reflects immunosuppression and needs treatment, but is not an emergency. Why e is unexpected: a creatinine rise on the class must be reported and the drug reviewed, without emergency intervention. Why f requires immediate follow-up: angioedema on this class is airway compromise. Why g requires immediate follow-up: hyperkalemia with peaked T waves is a rhythm emergency. Why h requires immediate follow-up: melena signals gastrointestinal bleeding, and corticosteroids raise that risk. The rule: airway, rhythm, and bleeding outrank everything metabolic on the same page.

Item 8 — Answers: 8a-2, 8b-1, 8c-1, 8d-2 Why 8a option 2 is right: fluoroquinolones block DNA gyrase and topoisomerase IV. Option 1 is a cephalosporin or penicillin mechanism, option 3 a tetracycline or aminoglycoside mechanism, option 4 a sulfonamide mechanism. Why 8b option 1 is right: the current label carries tendinitis and tendon rupture. Option 2 belongs to metformin, option 3 to propylthiouracil, option 4 to amiodarone. Why 8c option 1 is right: the labeled instruction is to stop the drug and contact the prescriber at the first sign of tendon pain. Option 2 continues the injury, option 3 masks it, option 4 is unsafe dosing practice for any drug. Why 8d option 2 is right: fluoroquinolones chelate divalent and trivalent cations. Option 1 does not affect absorption meaningfully, option 3 is unnecessary and unsafe, option 4 is not a labeled interaction. The rule: distractors on a cloze are pulled from neighboring classes, so the class you wrote down first is the answer key.

Item 9 — Answers: left wing 1 and 2, right wing 1 and 2 Why left 1 is right: continuing an anticoagulant during active intracranial bleeding worsens the bleed. Why left 2 is right: phytonadione plus four-factor prothrombin complex concentrate is the warfarin reversal pathway for major bleeding. Why left 3 is wrong: ambulating a client with suspected intracranial bleeding risks injury and delays reversal. Why left 4 is wrong: it administers more of the causative agent. Why left 5 is wrong: ice and a 4-hour delay treat a bruise, not a bleed. Why right 1 is right: neurologic deterioration is the earliest sign the bleed is expanding. Why right 2 is right: they measure whether reversal worked and whether blood loss continues. Why right 3 is wrong: weight tracks fluid, not bleeding. Why right 4 is wrong: bowel sounds are not the monitoring priority here. Why right 5 is wrong: glucose is unrelated to this scenario. The rule: in a bowtie, the wings must match the center; every action and every parameter answers to the condition in the middle.

Scoring logic. The matrix scores per row, so a single wrong cell costs one row and not the item. The cloze scores per blank. The bowtie scores per selected box, so leaving a wing incomplete guarantees lost points.

Margin notepartial credit means never leave a row blank. Tick boxes: matrix · cloze · bowtie. Reading a next-generation case → BOOK 01 · P60.

TakeawayNext-generation items score by cell, so a derived answer in every cell beats a confident guess in one.